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Transmission and pathogenicity of canine H3N2 influenza virus in dog and guinea pig models | Virology Journal

Influenza A virus causes respiratory disease in many animal species as well as in humans. Due to the high human-animal interface, the monitoring of canine influenza in dogs and the study of the transmission and pathogenicity of canine influenza in animals are important. Eight-week-old beagle dogs (Canis lupus familaris) (n = 13) were used for the intraspecies transmission model. The dogs were inoculated intranasally with 1 ml of 106 EID50 per ml of canine H3N2 influenza virus (A/canine/Thailand/CU-DC5299/2012) (CIV-H3N2). In addition, 4-week-old guinea pigs (Cavia porcellus) (n = 20) were used for the interspecies transmission model. The guinea pigs were inoculated intranasally with 300 µl of 106 EID50 per ml of CIV-H3N2. For the Thai CIV-H3N2 challenged in the dog model, the incoculated and direct contact dogs developed respiratory signs at 2 dpi. The dogs shed the virus in the respiratory tract at 1 dpi and developed an H3-specific antibody again ....

United States , New South Wales , Krung Thep Mahanakhon , National Laboratory Animal Center , Corbett Research , Chulalongkorn University Animal Care , Software For Statistics , Use Committee , Biosafety Level , One Step Quantitative , Data Science ,

People-centric projects are top priority for JICA in the Kingdom


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A Cambodian student takes the final practical exam for the higher diploma in electrical work. Photo supplied
People-centric projects are top priority for JICA in the Kingdom
Mon, 15 March 2021
The government’s goal of Cambodia becoming a high middle-income country by 2030 before reaching high-income status by 2050 could well become a reality given Cambodia’s stellar economic growth of 7.3 per cent over a decade, prior to the Covid-19 pandemic.
However, these ambitious targets can only be achieved by diversifying the Kingdom’s domestic economy and by developing human capital to support growth.
Towards this, the Japan International Cooperation Agency (JICA) has played a critical role in assisting the socio-economic development of Cambodia. ....

Svay Rieng , Phnom Penh , Siem Reap , Tonle Sap , Cambodia General , Kampong Cham , Mongkul Borey , Banteay Meanchey , National Career , Japan Official Development Assistance , Child Health Center , Ministry Of Environment , Ministry Of Health , Royal University Of Phnom Penh , Technology Agency , Institute Of Global Environmental Strategies , Department Of Labour Market Information , Tonle Sap Authority , Ministry Of Water Resources , Sustainable Development Goals , Yamagata University , Ministry Of Education , Community Outreach , Quality To Meet The Needs Of Industries , National Center , Human Resource Development System Of Co ,