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In a recent study published in Nature Communications, a team of researchers evaluated the variations between Gaussian and lattice light sheets related to beam homogeneity, axial precision, transverse resolution, and photo-bleaching, using computations and experimental measurements on fixed cells.
Researchers have developed a miniature microscope that is designed for high-resolution 3D images inside the brains of living mice. By imaging deeper into the brain than previously possible with miniature widefield microscopes, the new lightweight microscope could help scientists better understand how brain cells and circuits operate.