Orientation of magnet-directed spiral ganglion neurons - IJN
A) Representative fluorescent images of SGNs with different treatments. ( B) Average neurite length. ***p 0.001, ****p 0.0001 by one-way ANOVA. ( C) The neurite orientation index (cosθ). Cos ~1 for the neurites along the direction of magnetic force. *p 0.05 by one-way ANOVA. SPIO and SPIO+MF Promote the Development of Growth Cones We further determined the effect of the SPIO nanoparticles and the MF on SGN growth cones and synaptic density by immunofluorescence. We stained the cultured SGNs with the neuron marker anti-β tubulin and stained the actin-supported growth cone with phallo...