"Dexmedetomidine for hyperactive delirium at the end of life: An open-l" by Benjamin Thomas, Wing Shan Angela Lo et al.
Abstract Background: Terminal delirium, specifically the hyperactive delirium subtype at the end of life, is common in palliative care patients. Standard care often involves sedation to alleviate distress. The alpha -adrenoreceptor agonist dexmedetomidine may have promise in terminal delirium, due to its properties of decreasing delirium and permitting rousable sedation. Aim: This study aimed to describe the effect of dexmedetomidine on delirium and sedation, when delivered via continuous subcutaneous infusion (CSCI) in patients with terminal delirium. Design: The trial was prospectively regi...
Source: uow.edu.au