The incidence of artemisinin-resistant HRP2-negative malaria is increasing in Eritrea
1. In this drug efficacy study, the percentage of patients with malaria following artemisinin-based combination anti-malarial therapy increased steadily between 2016 and 2019. 2. Mutations in the Pkfelch13 gene were highly associated with resistance to artemisinin-based therapy as well as deletions of the hrp2 and hrp3 genes, which current histidine-rich protein 2 (HRP2) rapid diagnostic
Source: 2minutemedicine.com