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"Christchurch mutation" can block detrimental effects of Alzheimer's risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease. ....

New Zealand , Maxine Nelson , Robert Mahley , Yadong Huang , Gladstone Institutes , Gladstone Investigator Yadong Huang , Translational Advancement , Gladstone Investigator Robert Mahley , Lzheimer 39s Disease , Tau Protein ,

Worried about getting a blood test? 5 tips to make them easier (and still accurate)

For the majority of patients, blood collections are not a problem, just a minor inconvenience. Others may feel uneasy and anxious about the process. ....

Blood Flow , Blood Test ,

Developing a synthetic pathology framework: A step towards replacing animal testing

Researchers establish AnimalGAN as a reliable alternative for generating synthetic pathology data. ....

United States , Marques Shutterstock , Drug Administration , Nature Communications , Animal Generative Adversarial Network , United States Food , Modernization Act , Quantitative Structure Activity Relationship , Root Mean Square Error ,

Ram The King Without Ambition: Ramayana's Kabandha metaphor: Unraveling the curse of endless hunger in capitalism and socialism

The article draws a metaphor from the Ramayana, using the character Kabandha to represent the insatiable hunger and relentless growth associated with both Capitalism and Socialism. It explores how modern society praises endless ambition and the pursuit of wealth, framing contentment as a pathology. The author suggests that individuals, especially the affluent, are trapped in this hunger without permission to be satisfied. ....

Ram The King Without Ambition , Devdutt Pattanaik ,

UCLA researchers discover key step in cholesterol processing

UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream – potentially revealing a new pathway to target in cholesterol treatment. ....

Los Angeles , United States , Peter Tontonoz , University Of California , Laboratory Medicine , Los Angeles Health Sciences , Angeles Health , Biological Chemistry ,