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Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Researchers introduced and characterized a novel platform based on monoclonal antibodies (mAbs). ....

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Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments. ....

Ohio State University , United States , Konstantinos Karagiannis Sreenivas Gannavaram , Thalia Pacheco Fernandez , Aparna Bhattacharya , Megan Craig , Abhay Satoskar , Chaitenya Verma , Global Health Innovative Technology Fund , Ohio State University College Of Medicine , National Institute Of Allergy , Drug Administration , Ohio State University College , National Institute , Konstantinos Karagiannis , Sreenivas Gannavaram , Hira Nakhasi , Bone Marrow , Stem Cells ,

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

A new imaging agent, 68Ga-ABY-025, can predict early metabolic response to human epidermal growth factor receptor 2 (HER2)-targeted treatment in HER2-positive metastatic breast cancer patients, according to new research published in the September issue of The Journal of Nuclear Medicine. ....

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Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion. ....

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Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage. ....

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