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DNA building blocks regulate inflammation - Vimarsana News

DNA building blocks regulate inflammation

Credit: Hans-Georg Sprenger Mitochondria are the energy suppliers of our body cells. These tiny cell components have their own genetic material, which triggers an inflammatory response when released into the interior of the cell. The reasons for the release are not yet known, but some cardiac and neurodegenerative diseases as well as the ageing process are linked to the mitochondrial genome. Researchers at the Max Planck Institute for Biology of Ageing and the CECAD Cluster of Excellence in Ageing research have investigated the reasons for the release of mitochondrial genetic material and fou...

New drug inhibits the growth of cancer cells - Vimarsana News

New drug inhibits the growth of cancer cells

Credit: Hauke S. Hillen A newly developed compound starves cancer cells by attacking their "power plants" - the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read. Researchers from the Max Planck Institute for Biology of Ageing in Cologne, the Karolinska Institute in Stockholm and the University of Gothenburg report in their study that this compound could be used as a potential anti-tumour drug in the future; not only in mice but also in human patients. Mitochondria provide our cells with energy and cellular building blocks necessary ...

Novel principle for cancer treatment shows promising effect - Vimarsana News

Novel principle for cancer treatment shows promising effect

Researchers at Karolinska Institutet in Sweden report in the journal Nature that they have developed novel first-in-class inhibitors that compromise mitochondrial function in cancer cells. Treatment with the inhibitors stopped cancer cells from proliferating and reduced tumour growth in mice, without significantly affecting healthy cells. "We are excited to have shown that this novel principle for cancer treatment works in animal models and hopefully the inhibitors can now be developed further for anti-cancer treatment in humans," says Nils-Göran Larsson, professor at the Department of Medi...