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Alligator's mitazalimab shown to enhance cancer vaccine


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LUND, Sweden, May 5, 2021 /PRNewswire/
Alligator Bioscience (Nasdaq Stockholm: ATORX) today announced that preclinical data on its agonist anti-CD40 antibody mitazalimab has been published in the scientific journal Cancer Immunology, Immunotherapy.
The published data show that mitazalimab activates dendritic cells and tumor-reactive T cells resulting in enhanced anti-tumor efficacy in combination with a model cancer vaccine.
Title: The human anti-CD40 agonist antibody mitazalimab (ADC-1013; JNJ-64457107) activates antigen-presenting cells, improves expansion of antigen-specific T cells and enhances anti-tumor efficacy of a model cancer vaccine in vivo
Journal: Cancer Immunology, Immunotherapy
Authors: Adnan Deronic et al.
A publication in a prominent peer-reviewed journal such as Cancer Immunology, Immunotherapy is very encouraging and validates our findings. These data further highlight the strong potential for mitazalimab to be comb ....

Malin Carlsson , Adnan Deronic , Peter Ellmark , Aptevo Therapeutics Inc , Shanghai Henlius Biotech Inc , World Immunotherapy Congress , Nasdaq Stockholm , Cancer Immunology , Aptevo Therapeutics , Shanghai Henlius Biotech , மாலின் கார்ல்சன் , உலகம் நோயெதிர்ப்பு சிகிச்சை காங்கிரஸ் , நாஸ்டாக் ஸ்டாக்‌ஹோல்ம் , புற்றுநோய் நோயெதிர்ப்பு ,