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Reuters Reuters 21 July, 2021, 2:10 pm Vials labelled "Moderna, Johnson & Johnson, Pfizer-BioNTech coronavirus disease (COVID-19) vaccine" are seen in this illustration picture taken May 2, 2021. REUTERS/Dado Ruvic CHICAGO, July 20 (Reuters) – Scientists are working on a benchmark for COVID-19 vaccine efficacy that would allow drugmakers to conduct smaller, speedier human trials to get them to market and address a huge global vaccine shortage. Researchers are trying to determine just what level of COVID-19 antibodies a vaccine must produce to provide protection against the illness. Regulato...

Jul 21, 2021 CHICAGO – Scientists are working on a benchmark for COVID-19 vaccine efficacy that would allow drugmakers to conduct smaller, speedier human trials to get them to market and address a huge global vaccine shortage. Researchers are trying to determine just what level of COVID-19 antibodies a vaccine must produce to provide protection against the illness. Regulators already use such benchmarks — known as correlates of protection — to evaluate flu vaccines without requiring large, lengthy clinical trials. “You could use it to predict efficacy from a vaccine, which wi...

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Finding how much protection is enough when it comes to COVID-19 vaccines Alison Grande At Fred Hutch in Seattle, Dr. Peter Gilbert is working to find out how much of an immune response is enough to protect you from COVID-19. The measurement he is working to find is the “correlate of protection,” a measurement of the antibodies in the blood. Gilbert is a biostatistician who spent 20 years working on a vaccine for HIV. When the pandemic hit, he quickly shifted to work on COVID-19. “We learned expertise so that when the SARS-2 virus came along, we were ready to pivot and t...