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Dr Desai on the Evolution of Divarasib in KRAS G12C-mutated CRC

Jayesh Desai, MBBS, FRACP, discusses the evolution of divarasib, highlighting the rationale for combining the KRAS G12C inhibitor with cetuximab in patients with advanced colorectal cancer harboring KRAS G12C mutations in a phase 1b study.
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Jayesh Desai , Clinical Research , University Of Melbourne , Phasei Early Drug Development Program , Peter Maccallum Cancer Centre , Sir Peter Maccallum Department Of Oncology , Early Drug Development Program , Sir Peter Maccallum Department , Colorectal Cancer , Onclive Tv ,

Preliminary Data Show Improved Responses with Cetuximab Plus Divarasib in KRAS G12C–mutated CRC

Jayesh Desai, MBBS, FRACP, reports prior phase 1 data on the use of divarasib monotherapy in KRAS G12C–mutated CRC and early efficacy, safety, and presents pharmacokinetic data from the use of divarasib plus cetuximab from a phase 1 trial. ....

Roche Genentech , Pierre Fabre , Jayesh Desai , Astrazeneca Medimmune , Daiichi Sankyo Europe Gmb , Phasei Early Drug Development Program , University Of Melbourne , Merck Kga , Sir Peter Maccallum Department Of Oncology , Peter Maccallum Cancer Centre , Merck Kgaa , Boehringer Ingelheim , Bristol Myers Squibb , Early Drug Development Program , Peter Maccallum Cancer , Sir Peter Maccallum Department , Daiichi Sankyo Europe Gmbh , Cetuximab Plus Divarasib , Patients With Kras G12c Mutated Colorectal Cancer ,

Dr Desai on the Efficacy of Divarasib Plus Cetuximab in KRAS G12C–Mutant CRC

Jayesh Desai, MBBS, FRACP, discusses efficacy data for the combination of divarasib plus cetuximab in patients with colorectal cancer harboring a KRAS G12C mutation from a phase 1B study. ....

Jayesh Desai , Sir Peter Maccallum Department Of Oncology , Peter Maccallum Cancer Centre , Phasei Early Drug Development Program , University Of Melbourne , Clinical Research , Early Drug Development Program , Sir Peter Maccallum Department , Aacr Annual Meeting , Onclive Tv ,