Researchers devise more efficient, enduring CAR gene therapy to combat HIV
UCLA RESEARCH BRIEF National Institute of Allergy and Infectious Diseases (NIAID) The improved therapy engineers the body’s immune response against HIV rather than waiting for the virus — or parts of the virus — to induce a response. (Image: A T cell infected with HIV.) Enrique Rivero | FINDINGS A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule. This new approach to CAR T gene therapy — a type...