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A new experimental nanoparticle-based vaccine that has proven effective for flu, is also being tested for COVID-19 and studied as an HIV vaccine.

Preclinical Trials Demonstrate the Efficacy of Nanoparticle-Based Vaccine Written by AZoNanoMay 25 2021 Preclinical studies have demonstrated the effectiveness of an experimental flu vaccine that contains scores of microscopic spherical sacs carrying infection-fighting proteins all through the body. The circle-shaped objects in the image above are cobalt-porphyrin-phospholipid (CoPoP) nanoparticles decorated with flu proteins. Image Credit: University at Buffalo. As explained in a study recently published in the Proceedings of the National Academy of Sciences on May 24 th, 2021, the experime...

Nanoparticle based shot could boost efficacy, accelerate production of seasonal flu vaccines Seasonal flu vaccines typically work 40-60% of the time, according to the US Centers for Disease Control and Prevention (CDC). An experimental recombinant protein nanoparticle vaccine that stimulates a strong immune response is hoping to address that inefficiency. Key to the vaccine's success is a liposome the developers created called cobalt-porphyrin-phospholipid, or CoPoP. They are tiny spherical sacs, which are small enough to be considered nanoparticles, and they form...

Jonathan Lovell, associate professor Department of Biomedical Engineering An experimental flu vaccine consisting of billions of tiny spherical sacs that carry infection-fighting proteins throughout the body has proven effective in preclinical studies. Described in a study published May 24 in the Proceedings of the National Academy of Sciences, the vaccine has the potential to: Improve the effectiveness of seasonal flu vaccines, which typically work 40-60% of the time, according to the U.S. Centers for Disease Control and Prevention. Take less time to produce large quantities because, unlike m...