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Loading video... VIDEO: A low-resolution time-lapse of a mitochondrial network (cell's powerhouse) inside a cancer cell (left) is enhanced using artificial intelligence (right). Inset at bottom left highlights a fission (splitting) event that... view more  Credit: Salk Institute/Waitt Advanced Biophotonics Core LA JOLLA--(March 8, 2021) Deep learning is a potential tool for scientists to glean more detail from low-resolution images in microscopy, but it's often difficult to gather enough baseline data to train computers in the process. Now, a new method developed by scientists at the S...

In this scenario, the present study aimed to evaluate a possible association of estrogen receptor α polymorphisms with dementia in a Brazilian cohort. The genotyping for the ERα PvuII and XbaI polymorphisms were performed by polymerase chain reaction-restriction fragment length polymorphism. The ERα PvuII pp genotype was associated with a higher odds ratio for dementia (OR = 3.42, 95% CI = 1.33-8.77, p = 0.01, in a model including covariates. A linear regression model identified significant associations of the ERα PvuII genotypes with CDR scale , β = 0.26 and p = 0.001. In conclusion, es...

Neurons are the primary cells of the nervous system, and the signals that are transmitted between them are responsible for all our actions and our cognitive ability.

Optogenetics, or genetically engineering neurons to respond to light, is an important technique for studying how neurons work. However, manipulating individual synapses (gaps between neurons), where signaling transmission occurs, has been challenging until now. Researchers at National Institute of Physiological Sciences, Japan, have now generated a light-activated signaling protein that can help study signaling-related physiological changes in single neurons--a breakthrough that will be valuable for neuroscience.

News Author: Anna-Mart Engelbrecht Thursday (4 February) is World Cancer Day. In an opinion piece for Health24, Prof Anna-Mart Engelbrecht (Department of Physiological Sciences) writes about how advances in personalised medicine and biotechnology offer new hope for cancer patients. Re​ad the article below or click Anna-Mart Engelbrecht* Each year on February 4 th, World Cancer Day raises awareness about cancer as a critical health issue that we cannot dare to neglect. The global cancer burden is increasing rapidly in developing countries as population numbers continue to grow and life ex...