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Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

The brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain.

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Discovery: Faulty DNA Disposal System Linked to Inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from the cell’s nuclear DNA that mitochondria use to create life-giving energy. When mtDNA remains where i

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Research: Fish Protection Can Coexist with Human Welfare

Research: Fish Protection Can Coexist with Human Welfare
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Protecting fish doesn't have to mean neglecti

<p>With fish stocks declining globally, more than 190 countries recently made a commitment to protect a third of the world’s oceans within “Marine Protected Areas,” or MPAs by 2030. MPAs that ban fishing have the biggest conservation impact, but can come at a huge cost to coastal and Indigenous communities. Nonetheless, it isn’t an all or nothing game, according to a new analysis.</p>

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Inflammation Linked to Faulty DNA Disposal System

Inflammation Linked to Faulty DNA Disposal System
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Faulty DNA disposal system causes inflammatio

<p>Salk scientists discovered a pathway from mitochondrial DNA replication stress to immune system activation and inflammation, finding that endosomes responsible for disposing of dysfunctional mitochondrial DNA were leaking mitochondrial DNA into the cell and prompting the inflammatory immune response. The pathway provides new targets for therapeutics that disrupt inflammation during aging and disease.</p>

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Lung cancer hijacks immune cell metabolism to fuel its own growth

Lung cancer hijacks immune cell metabolism to fuel its own growth
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Mitochondrial misfire sparks inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA-;a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy.

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Faulty DNA disposal system causes inflammation

Faulty DNA disposal system causes inflammation
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Faulty DNA disposal system causes inflammatio

Faulty DNA disposal system causes inflammatio
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