Genetic risk scores 'do not have a place in public health screening'
Researchers said the scoring system led to false positives and ‘performed poorly' when predicting if a person would develop common diseases.
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Researchers said the scoring system led to false positives and ‘performed poorly' when predicting if a person would develop common diseases.
<p>The new study, published in <em>BMJ Medicine</em>, looked at 926 polygenic risk scores for 310 diseases. It found that, on average, only 11% of individuals who develop disease are identified, while at the same time 5% of people who do not develop the disease test positive. Unaffected people usually outnumber those affected which results in far more false than true positive predictions.</p>
Researchers said the scoring system led to false positives and ‘performed poorly’ when predicting if a person would develop common diseases.
Researchers said the scoring system led to false positives and ‘performed poorly’ when predicting if a person would develop common diseases.
Researchers said the scoring system led to false positives and ‘performed poorly’ when predicting if a person would develop common diseases.