"Comment on "assessing the extent of bone bioerosion in short timescale" by Justyna J. Miszkiewicz, Janna M. Andronowski et al.
We outline issues with a recent publication by Mein and Williams (2023), which is primarily based on the morphology and quantification of osteocyte lacunae, microscopic cavities that house cells (osteocytes) which sustain bone tissue in living vertebrates. Using 26 rats (Rattus rattus) of unreported age and sex, the authors propose a method whereby post-mortem bone degradation on a short timescale can be quantified by analysing subtle shape changes of osteocyte lacunae. However, a lack of consideration is given to the natural variation and other biological factors influencing osteocyte lacunar...