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Multigene Assays Advance Genetic Testing in Breast Cancer, Drive Personalized Medicine

Multigene assays allow for patients to receive personalized breast cancer treatment by identifying promising therapeutic targets, which could improve patient clinical outcomes in the long term and help providers better understand tumor biology. ....

United States , David Carillet , Image Credit , Prediction Analysis ,

Dr Hafez on the Influence of Biomarker Expression on Adjuvant T-DM1 Use in HER2+ Breast Cancer

Maria Hafez, MD, discusses differences in biomarker expression prior to and following neoadjuvant chemotherapy treatment in HER2-positive breast cancer. ....

Maria Hafez , Breast Cancer Clinical Research , Sidney Kimmel Medical College , Thomas Jefferson University , Sidney Kimmel Cancer Center , Prediction Analysis , Absolute Intrinsic Molecular Subtyping , Early Stage Her2 Positive Breast Cancer ,

Exploratory Analyses of KATHERINE Trial Inform Adjuvant T-DM1 Use in HER2+ Breast Cancer

Maria Hafez, MD, spotlights the KATHERINE trial in HER2-positive breast cancer, expanding on the respective toxicity profiles of T-DM1 and trastuzumab that were identified in an exploratory safety analysis of the trial; updated outcomes with T-DM1 in those with residual invasive disease after neoadjuvant treatment and surgery; and more. ....

United States , Maria Hafez , Sidney Kimmel Medical College , Science Summit , Breast Cancer Clinical Research , Sidney Kimmel Cancer Center , Thomas Jefferson University , Prediction Analysis , Absolute Intrinsic Molecular , Katherine Trial , Her2 Positive Breast Cancer , Breast Cancer , Ado Trastuzumab Emtansine , T Dm1 , Sidney Kimmel Cancer Center , Thomas Jefferson University ,

Research suggests that estrogen-related gene expression may influence postmenopausal breast cancer risk and prevention strategies

Research suggests that estrogen-related gene expression may influence postmenopausal breast cancer risk and prevention strategies
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United States , Priscilla Furth , Georgetown Lombardi Comprehensive Cancer Center , American Journal , Georgetown Lombardi , Prediction Analysis ,