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RESPONSE: Seladelpar Normalizes Alkaline Phosphatase, Reduces Pruritus in PBC - Vimarsana News

RESPONSE: Seladelpar Normalizes Alkaline Phosphatase, Reduces Pruritus in PBC

Results from the phase 3 trial showed seladelpar elicited biochemical response, normalized alkaline phosphatase, and reduced pruritus at a greater rate than placebo.

Tharimmune Announces Initiation of Phase 1 Clinical Trial of TH104 and Provides Business Update - Vimarsana News

Tharimmune Announces Initiation of Phase 1 Clinical Trial of TH104 and Provides Business Update

Phase 1 trial initiated to assess safety/tolerability and absolute bioavailability of TH104 with topline data expected in 2Q24Planning well underway for Phase 2 of TH104 in primary biliary cholangitis (PBC) patients suffering from moderate-to-severe chronic pruritusCompany outlines near-clinical pipeline of novel an...

Cholangiocyte Biology and Its Implications in Cholangiopathies - Vimarsana News

Cholangiocyte Biology and Its Implications in Cholangiopathies

This article focuses on cholangiocyte biology and incidence of cholangiopathies.1

Bradley B. Zollner | News, Sports, Jobs - Vimarsana News

Bradley B. Zollner | News, Sports, Jobs

March 7, 1960-Jan. 15 2024 NEW ULM—Bradley B. Zollner, age 63, of New Ulm died Monday, January 15, 2024, at the University of Minnesota Medical Center in Mi

Seladelpar Reduces Serum IL-31, Improves Pruritus in Patients with Primary Biliary Cholangitis - Vimarsana News

Seladelpar Reduces Serum IL-31, Improves Pruritus in Patients with Primary Biliary Cholangitis

The post-hoc analysis of the phase 3 ENHANCE study provides the first published evidence of a correlation between decreases in IL-31, bile acids, and pruritus symptoms in PBC following treatment with an investigational agent.