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Aprea Therapeutics Announces Results of Primary Endpoint from Phase 3 Trial of Eprenetapopt in TP53 Mutant Myelodysplastic Syndromes (MDS) | Small Molecules - Vimarsana News

Aprea Therapeutics Announces Results of Primary Endpoint from Phase 3 Trial of Eprenetapopt in TP53 Mutant Myelodysplastic Syndromes (MDS) | Small Molecules

Hits: 1013 The trial failed to meet its primary endpoint of complete remission (CR) rate CR rate was 53% higher in eprenetapopt with AZA arm compared to AZA alone, but did not reach statistical significance BOSTON, MA, USA I December 28, 2020 I Aprea Therapeutics, Inc. (Nasdaq: APRE), a biopharmaceutical company focused on developing and commercializing novel cancer therapeutics that reactivate the mutant tumor suppressor protein, p53, today announced results of the primary data cut from its Phase 3 clinical trial evaluating the safety and efficacy of eprenetapopt with azacitidine (AZA) v...

KITE'S TECARTUS®▼ (AUTOLOGOUS ANTI-CD19-TRANSDUCED CD3+ CELLS) GRANTED CONDITIONAL MARKETING AUTHORISATION FOR THE TREATMENT OF ADULT PATIENTS WITH RELAPSED OR REFRACTORY MANTLE CELL LYMPHOMA AFTER TWO OR MORE LINES OF SYSTEMIC THERAPY INCLUDING A BRUTON'S TYROSINE KINASE (BTK) INHIBITOR - Vimarsana News

KITE'S TECARTUS®▼ (AUTOLOGOUS ANTI-CD19-TRANSDUCED CD3+ CELLS) GRANTED CONDITIONAL MARKETING AUTHORISATION FOR THE TREATMENT OF ADULT PATIENTS WITH RELAPSED OR REFRACTORY MANTLE CELL LYMPHOMA AFTER TWO OR MORE LINES OF SYSTEMIC THERAPY INCLUDING A BRUTON'S TYROSINE KINASE (BTK) INHIBITOR

utologous anti CD19 transduced CD3+ cells Granted Conditional European Marketing Authorisation for Relapsed and Refractory Mantle Cell Lymphoma --   London, UK – 16 December 2020 – Kite, a Gilead Company, today announced that the European Commission has granted conditional marketing authorisation for its autologous anti CD19 transduced CD3+ cells, a chimeric antigen receptor (CAR) T cell therapy, as a treatment for adult patients with relapsed or refractory mantle cell lymphoma after two or more lines of systemic therapy including a Bruton’s tyrosine kinase (BTK) inhibitor.   The con...