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New drug shows promise against pancreatic, breast cancers - Vimarsana News

New drug shows promise against pancreatic, breast cancers

A study in A second study, published in the Journal of Experimental Medicine, shows the drug’s effectiveness against triple-negative breast cancer, a fast-growing and hard-to-treat type of breast cancer that carries a poor prognosis. Zhi-Ren Liu, a biology professor at Georgia State University, created ProAgio from a human protein to target the cell surface receptor integrin αVβ₃, which is expressed on cancer-associated fibroblasts. Fibroblasts are cells that generate collagen and other fibrous molecules which tumors can mobilize into service, creating a thick, physical barrier known ...

Drug is promising against pancreatic and breast cancers - Vimarsana News

Drug is promising against pancreatic and breast cancers

The drug is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology. A second study, published in the Journal of Experimental Medicine, shows the drug is also effective against triple-negative breast cancer, a fast-growing and hard-to-treat type of breast cancer that carries a poor prognosis. Clinical trials are set to begin in 2021.