University of Glasgow: ACCUMULATION OF INFECTED RED BLOOD CELLS KEY TO DEVELOPMENT OF CEREBRAL MALARIA
Share White adipose tissue (WAT), or white fat, plays a fundamental role in the development of cerebral malaria in mouse models and humans, according to a new study led by Harvard T.H. Chan School of Public Health scientists in collaboration with the University of Glasgow and an international team of researchers. The study details the process by which red blood cells infected with malaria-causing Plasmodium parasites are sequestered in small blood vessels throughout WAT, where they stimulate the production of the hormone leptin via a well-studied nutrient-sensing pathway known as mTORC1. The ...