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AB Science announces the publication of an article in the world-renowned journal Science that confirms potential of masitinib as a treatment of Covid-19 with anti-viral activity against SARS-CoV-2 and all tested variants of concern


AB Science SA (Euronext - FR0010557264 - AB) today announces publication of a peer-reviewed article titled ‘
Masitinib is a broad coronavirus 3CL inhibitor that effectively blocks replication of SARS-CoV-2 in the journal
Science [1]. The article reports on research that identifies masitinib as a broad antiviral agent capable of treating SARS-CoV-2 (the virus that causes COVID-19), including demonstration of
in vivo activity in mice, with efficacy maintained,
in vitro, against SARS-CoV-2 variants of concern.
This article and its accompanying online supplemental material are accessible online from the journal website: https://science.sciencemag.org/lookup/doi/10.1126/science.abg5827
Research led by Professor Savas Tay and Dr. Nir Drayman from the Pritzker School for Molecular Engineering (University of Chicago, USA) screened a library of 1,900 clinically safe drugs and identified masitinib as the most potent inhibitor of the main target responsible for ....

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AB Science announces that a new independent publication confirms that masitinib has anti-vital ...


Press release content from Globe Newswire. The AP news staff was not involved in its creation.
AB Science announces that a new independent publication confirms that masitinib has anti-vital .
AB ScienceJanuary 25, 2021 GMT
NEW INDEPENDENT PUBLICATION CONFIRMS THAT MASITINIB HAS ANTI-VIRAL ACTIVITY AGAINST THE SARS-COV-2 VIRUS
IN VITRO AND IS A PROMISING CANDIDATE FOR TREATING COVID-19
Paris, 25 January 2021, 8.30am CET
AB Science SA (NYSE Euronext - FR0010557264 - AB) today announced the publication of preclinical study results with masitinib in COVID-19. Research led by scientists from the Institute of Human Virology (Guangzhou, China) has been published in the peer-reviewed journal
mBIO (a journal of the American Society for Microbiology). The article, entitled ‘Engineering a reliable and convenient SARS-CoV-2 replicon system for analysis of viral RNA synthesis and screening of antiviral inhibitors’,[1] is freely accessible online from the mBio ....

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