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Spotlight on Dr. Melody Campbell, "Imaging Proteins to Understand Their Function". Dr. Campbell is an expert in using cryogenic electron microscopy, or cryo-EM, a microscopy technique that allows scientists study the structure of proteins without first crystallizing them.
Flow cytometry is a useful analytical tool that can detect cells' characteristics within a population. This article looks at its role in protein engineering.
Investegate announcements from https://immatics.com/, Immatics Announces Full Year 2021 Financial Results and Corporate Update
IMA203 TCR-T candidate targeting PRAME demonstrated a 50% objective response rate across different solid tumor types in an interim update of Phase 1a dose escalationMultiple IMA203 Phase
To overcome the hurdle of two technologies used to determine the structure and function of proteins—X-ray crystallography and cryogenic electron microscopy— researchers at Stanford University's Schools of Medicine and Engineering and the Department of Energy's SLAC National Accelerator Laboratory have used a kind of molecular cage to stabilize certain medium-sized proteins so they can be imaged with cryo-EM.