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New therapeutic target for Huntington's treatment


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IMAGE: From left to right: Mercè Masana, Ana Gámez-Valero, Eulàlia Martí, Anna Guisado-Corcoll, Esther Pérez-Navarro and Maria Solaguren-Beascoa.
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Credit: UNIVERSITY OF BARCELONA
Huntington s disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations. The origin of this disease has been associated with the anomalous functioning of the mutated protein: mHTT, but recent data showed the involvement of other molecular mechanisms.
A new study conducted by the University of Barcelona has identified a type of ribonucleic acid (RNA) as a potential therapeutic target for the treatment of the disease. These are the small RNA, or sRNAs, molecules that do not code proteins but have important functions in the regulation of gene expression. According to the study, sRNAs would take part in the development of the disease, results that shed light on the design ....

Comunidad Autonoma De Cataluna , Acta Neuropathologica , University Of Barcelona , University Medical Center , Health Sciences Eul , Biomedical Research Networking Center On Neurodegenerative Diseases , Institute Of Neurosciences , Pii Sunyer Biomedical Research Institute , Public Health Networking Biomedical Research Centre , Biomedical Research Networking Center , Neurodegenerative Diseases , Sunyer Biomedical Research Institute , Genomic Regulation , Medicine Health , Pharmaceutical Science , Gene Therapy , Disease In The Developing World , காமுனிடட தன்னாட்சி டி கடலுள் , பல்கலைக்கழகம் ஆஃப் பார்சிலோனா , பல்கலைக்கழகம் மருத்துவ மையம் , நிறுவனம் ஆஃப் நரம்பியல் , பொது ஆரோக்கியம் நெட்வொர்க்கிங் உயிர் மருத்துவ ஆராய்ச்சி மையம் , உயிர் மருத்துவ ஆராய்ச்சி நெட்வொர்க்கிங் மையம் , மருந்து ஆரோக்கியம் , மருந்து அறிவியல் , கீந் சிகிச்சை ,

Study identifies potential therapeutic target for treatment of Huntington's disease