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G), invasion rate ( H, I) in vitro model of LNCap cell. *p 0.01 compared with negative group, #p 0.01 compared with down-regulation of RAMS11 group. Abbreviations: Negative, negative mimics group; SiRAMS11, down-regulation of RAMS11 group; Top2α, over-expression of Top2α group. Discussion The treatment of prostate cancer is mainly determined by objective factors, including patient age, physical condition, clinical stage, Gleason score, presence or absence of pelvic lymph nodes, distant metastases, and life expectancy. 18 At present, there are various therapeutic methods for prostate cancer...

Methods and Data Tissue Samples A total of 66 cases of OS patients treated in Yantai Affiliated Hospital of Binzhou Medical University from January 2010 to January 2014 were collected. Cancer tissues and paracancerous tissues of the patients were collected during the operation, transported with liquid nitrogen and sent to the laboratory for testing. The tissues were stored at −80°C. Peripheral blood (3 mL) was collected from patients preoperatively, and peripheral blood (3 mL) was also collected from 66 cases of healthy subjects simultaneously. The obtained peripheral blood was placed in t...

1 1Medical Oncology Department of Thoracic Cancer (2), Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang 110042, Liaoning, People’s Republic of China; 2Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, Liaoning, People’s Republic of China Correspondence: Rui Ma Medical Oncology Department of Thoracic Cancer (2), Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang 110042, Liaoning, People’s Republic of China Background: Lung cancer is one of the most aggressive tumors with high incid...