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Scientists identify drugs with potential to stop plaque buildup in arteries ANI | Updated: Feb 25, 2021 23:26 IST Ottawa [Canada], February 25 (ANI): A new clinical study led by researchers of the University of Alberta claim to have found better treatments for cardiovasculardisease, the second leading cause of death in Canada. The researchers identified a new mechanism responsible for the buildup of plaque on artery walls, a process known as atherosclerosis. This plaque, made up of fats, cholesterol and other substances, can restrict blood flow and is a major factor in cardiovasculardisease. We identified a new mechanism underlying atherosclerosis, explained Chris Cairo, a professor in the Department of Chemistry and co-lead author of the new study. We also demonstrated that this can be addressed pharmacologically. Using inhibitors developed in our lab, we found that this could be a new strategy for therapeutics in cardiovasculardisease.

Al qahirahTianlin guoWarren wakarchukAlexey pshezhetskyRadhika chakrabortyDepartment of chemistryUniversity of albertaDepartment of biological sciencesCanadian network centre of excellenceChris cairoCanadian network centreBiological sciencesராதிகா சக்ரவர்த்திதுறை ஆஃப் வேதியியல்பல்கலைக்கழகம் ஆஃப் ஆல்பர்ட்டாதுறை ஆஃப் உயிரியல் அறிவியல்