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Clinical Challenges in MS: Addressing Radiologically Isolated Syndrome

Is this earliest of stages a chance to intervene early, or too uncertain to treat?

University of texas southwestern medical centerUnited statesJohn corboyIde smetsDarin okudaErasmus medical centerUniversity of coloradoTexas southwestern medical centerMultiple sclerosisRadiologically isolated syndromeClinically isolated syndromeSpinal fluid

Clinical Challenges: Test Your Knowledge of MS

A three-question quiz on stopping therapy, family planning, and radiologically isolated syndrome

Medpage today clinical challengesRadiologically isolated syndromeFamily planningMultiple sclerosis

Teriflunomide Delays MS Progression in Patients With Radiologically Isolated Syndrome

Teriflunomide, compared with placebo, leads to a greater risk reduction in preventing a first clinical event in patients with RIS.

Radiologically isolated syndrome

New Evidence Early Tx Improves Preclinical MS Outcomes

The disease-modifying drug teriflunomide reduces the risk of developing clinical multiple sclerosis by 72% in radiologically isolated syndrome.

Christine lebrunUniversity of niceSyndrome consortiumUniversity coteUniversity hospital of niceRadiologically isolated syndromeChristine lebrun frUniversity hospitalMultiple sclerosis msMultiple sclerosisClinical researchClinical trialsLinical studiesLiver enzymesLiver studiesCentral nervous system

Teriflunomide Inhibits Clinical Demyelinating Event in Patients With MS

Teriflunomide treatment incurred an unadjusted risk reduction of 63% and an adjusted risk reduction of 72% in inhibiting a first clinical demyelinating event in patients with multiple sclerosis (MS).

Radiologically isolated syndromeMulticenter randomized double blinded assessmentFirst attackMultiple sclerosisClinical demyelinating eventRisk reduction

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