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Scientists have described and developed 3D models that recreate how an essential transcription factor, related to the progression of lung cancer and some types of leukemia in adults, binds to specific points in the genome to perform its function. ....
Transcription factors are proteins that interact with DNA to regulate the function of some genes. Generally, a single transcription factor binds to several regions in the genome as it orchestrates complex cellular responses, which require the activation or inhibition of several genes. ....