One-step method to generate mice for vaccine research
E-Mail BOSTON -- To develop vaccines and investigate human immune responses, scientists rely on a variety of animal models, including mice that can produce human antibodies through genetically engineered B cell receptors, which are specialized antibodies bound to the B cell membrane. These mice, however, often take several years to develop, requiring a complicated process of genetic modification and careful breeding. "The time it takes to generate these specialized mice has been a major factor in delaying vaccine development," says Facundo Batista, PhD, associate director of the Ragon Inst...
Source: eurekalert.org