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Bariatric surgery may improve rates for spontaneous ovulation in patients with polycystic ovarian syndrome and obesity

1. Women in the surgical group reported 2.5 times more spontaneous ovulations than in medical therapy. 2. Those assigned to surgery had a higher rate of adverse events, although none led to long-term issues. Evidence Rating Level: 1 (Excellent) Study Rundown: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility and obesity ....

United Kingdom , Lifestyle Program In Obese Infertile Women , Rating Level , Randomized Trial , Lifestyle Program , Obese Infertile , Between Feb ,

SGLT2 inhibitors improved outcomes in stage five chronic kidney disease

1. In this retrospective cohort study, among patients with type 2 diabetes (T2D) and stage five chronic kidney disease (CKD), the use of a sodium-glucose cotransporter-2 inhibitor (SGLT2i) was associated with a lower risk of dialysis, cardiovascular events, diabetic ketoacidosis (DKA), and acute kidney injury (AKI). 2. SGLT2i use was not associated with a difference ....

Taiwan National Health Insurance Research Database , Minute Medicine Inc , Rating Level , National Health Insurance Research Database ,

Transcatheter aortic valve implantation non-inferior to surgical replacement in low-to-intermediate risk patients

1. In this randomized controlled trial, it was found that those who received transcatheter aortic valve replacement (TAVI) did not have an increased risk of stroke and all-cause mortality compared to those who received surgical replacement (SAVR). 2. Those who underwent a transcatheter procedure had significantly fewer major bleeding events compared to those who underwent ....

Minute Medicine Inc , Rating Level ,

Short-term androgen deprivation therapy does not improve survival in patients receiving postoperative radiotherapy for prostate cancer

1. There was no significant difference in metastasis-free survival between the ADT and non-ADT groups over 10 years. 2. Adverse events were comparable between both groups and no fatalities were reported. Evidence Rating Level: 1 (Excellent) Study Rundown: Short-term androgen deprivation therapy (ADT) with primary adjuvant radiotherapy is known to improve metastasis-free survival in patients ....

United Kingdom , Rating Level , Castration Sensitive Prostate , Between Nov ,

Patient education programs may reduce disability and symptoms of chronic pain

1. Adults with chronic low back pain (CLBP) randomized into a 6-week pain intervention education program were observed to have significantly relieved burden of pain-related disability and overall pain intensity when combined with the physiotherapeutic standard of care. 2. Measures of self-reported well being also improved significantly more in the pain education group compared to ....

World Health Organization , Institute Of Medical Sciences , Rating Level , Shere Kashmir Institute , Medical Sciences , Roland Morris Disability Questionnaire , General Self Efficacy Scale , Five Well Being Index ,