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And the number of people vaccinated is not where it should be. reporter: the delta variant already driving a nationwide surge. and officials fear teams on the front lines will be soon pushed to their breaking point. we re exhausted by the knowledge that we are the duct tape that is preventing a complete collapse of the health care system. reporter: health officials stress, the booster shots offer the best protection against delta and omicron. the first real world study of omicron in south africa showed that two doses of the pfizer vaccine are just 33% effective against infection, but 70% effective against severe illness. and hospitalizations linked to omicron in south africa were 29% lower compared to delta. the disease seems to be less severe. whether it is inherently less pathogenic as a virus or whether there is more protection in the community, we re going to have to see when it comes in the united states. reporter: and tonight, the most promising news yet on pfizer s ant ....