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Real-World Data Confirm Efficacy of Dupilumab in Severe EoE

Dupilumab demonstrated real-world efficacy in patients with severe, treatment-refractory fibrostenotic eosinophilic esophagitis, most of whom would not have qualified for prior clinical trials. ....

Christopher Lee , Evan Dellon , University Of North Carolina , Esophageal Diseases , North Carolina , Chapel Hill , Clinical Gastroenterology , Nt Ears , Eosinophilic Esophagitis , Osinophil Granulocytes ,

FDA Updates Indications for Temozolomide

This is the second drug to receive a labeling update under the agency s Project Renewal program, which aims to keep labels of older cancer drugs up to date with current practice. ....

Drug Administration , Project Renewal , Patient Information , Malignant Head And Neck Neoplasm , Colorectal Cancer , Alignant Neoplasia , Colon Cancer , Alignant Colon Neoplasm , Malignant Rectal Neoplasm , Rectal Cancer , Ancer Rectal , Us Food And Drug Administration , Nited States Food And Drug Administration , Combination Chemotherapy , Doctor Patient Relationship Counseling , Hysician Patien ,

Is Additional Treatment Needed Pretransplant in R/R AML?

Experts recently debated whether additional intensive therapy can improve posttransplant outcomes for patients with acute myeloid leukemia who have residual disease after induction therapy. ....

United States , Fred Hutchinson , Mikkaela Sekeres , Johannes Schetelig , Ronaldb Walter , University Of Miami Miller School Medicine , Fred Hutchinson Cancer Research Center , American Society Of Hematology , Society Of Hematologic Oncology , Hematologic Oncology , Clinical Trials Unit , Miami Miller School , American Society , Complete Remission , Annual Meeting , Acute Leukemia , Transplantation Stem Cell , Ransplantation Hematopoietic Stem Cell , Hematopoietic Stem Cell Transplantation , Stem Cell Transplantation , Stem Cell Therapy , Herapy Stem Cell , Residual Disease , Acute Myeloblastic Leukemia , Myelodysplastic Syndrome ,

Pulsed Field Ablation Challenges Conventional Devices in AF

In the ADVENT trial, pulsed field ablation, a new technology for terminating drug-refractory paroxysmal AF, was noninferior to conventional thermal ablation but had potential advantages. ....

New York , United States , Viveky Reddy , Biosense Webster , Arrhythmia Services , Gentofte University Hospital , European Society Of Cardiology , Boston Scientific , Cardiac Arrhythmia Services , Mount Sinai Hospital , European Society , New England Journal , Presented August , Atrial Fibrillation , F Atrial Fibrillation , Catheter Ablation , Erebrovascular Accident , Va Cerebrovascular Accident , Healthcare And Medical Technology , Ealth And Medical Tech , Ealth And Med Tech , Ealth And Medical Technology ,

ReCor Renal Denervation System Safe, Effective: FDA Panel

The ReCor renal denervation system for treating refractory hypertension is safe and effective but further study is needed in vulnerable subpopulations, an FDA advisory panel concludes. ....

United States , Rush University , Deneen Hesser , Janet Wittes , John Somberg , Keith Allen , Jim Blankenship , Mark Lockhart , Benjamin Saville , John Hirshfeld Jr , University Of New Mexico , Circulatory System Devices Panel , Division Of Cardiology , Drug Administration , University Of Pennsylvania Perelman School Medicine , University Of Alabama , Recor Paradise Ultrasound Renal Denervation , Precor Inc , Mid America Heart , Lung Surgeons , Kansas City , New Mexico , Pennsylvania Perelman School , Simplicity Spyral Renal Denervation System , Renal Denervation , Cardiovascular Imaging ,