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Merck's Bintrafusp Alph Monotherapy In Biliary Cancer Misses Threshold For Regulatory Filing


Merck s Bintrafusp Alph Monotherapy In Biliary Cancer Misses Threshold For Regulatory Filing
BERLIN (dpa-AFX) - Merck KGaA (MKGAY.PK) Tuesday announced a single agent efficacy second-line treatment using bintrafusp alpha monotherapy in locally advanced or metastatic biliary tract cancer or BTC patients. However, the study missed the pre-defined threshold that would have enabled regulatory filing for BTC in the second-line setting.
The study enrolled 159 patients, who have failed or are intolerant of first-line platinum-based chemotherapy.
The results demonstrated single-agent efficacy and durability with a manageable safety profile after more than nine months of follow-up.
The company said the Phase II/III study of bintrafusp alfa in combination with chemotherapy is the first-line treatment for BTC. ....

Merck Kga , மெர்க் க்க ,

Nutra Pharma Corporation: Nutra Pharma Engages Quality and Regulatory Professionals Ahead of Clinical Trials


Nutra Pharma Corporation: Nutra Pharma Engages Quality and Regulatory Professionals Ahead of Clinical Trials
Nutra Pharma is providing updates on their work in improving capabilities and certifications in their laboratory for drug production and validation in preparation of expanded OTC sales and clinical trials
Plantation, Florida (Newsfile Corp. - March 11, 2021) - Nutra Pharma Corporation (OTC Pink: NPHC), a biotechnology company marketing Nyloxin®, Pet Pain-Away and Equine Pain-Away in the over-the-counter (OTC) pain management market and which is also developing treatments for Multiple Sclerosis (MS), Human Immunodeficiency Virus (HIV) and Pain, is providing updates today on their work in improving their existing facilities for manufacturing and validation of their drug products; including their technologies for the treatment of Multiple Sclerosis (MS) and potential countermeasures against nerve agents like sarin gas and VX. As part of this process, Nutra Pharma tod ....

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Falcon Gold Corp: Falcon Reports Regulatory Acceptance of Option Agreement on Esperanza Gold/Silver/Copper Project in La Rioja, Argentina


Falcon Gold Corp: Falcon Reports Regulatory Acceptance of Option Agreement on Esperanza Gold/Silver/Copper Project in La Rioja, Argentina
FALCON GOLD CORP.
(FG:TSX-V), (3FA:GR), (FGLDF:OTC PINKS); ( Falcon or the Company ) is pleased to report the TSX Venture Exchange has accepted and approved the option to acquire up to a 100% interest in the Esperanza Gold, Silver, Copper minerals concessions located in La Rioja Province, Argentina.
The New Option Agreement
Under the Agreement to earn its initial 80% interest, the Company has agreed to make payments to the Vendors over a four-year option period totalling 500,000 Falcon common shares and 500,000 share purchase warrants. Each Warrant will entitle the Vendor to purchase one Falcon common share for a period of 12 months for a purchase price set on each date of issue at 125% of the closing price for Falcon shares traded on the Toronto Venture Exchange. During the four-year option period, Falcon is to make minimum ex ....

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