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I mpact of linzagolix treatment on anemia in women with uterine fibroid related heavy menstrual bleeding:  results of two P hase 3 clinical trials Lead author: William Catherino, MD, PhD; Professor, Department of Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences Key Conclusions: High and low linzagolix doses with and without ABT improved hemoglobin and ferritin levels in anemic women with uterine fibroids.  In the 12-week follow-up period hemoglobin levels decreased but did not return to baseline levels. Poster : Safety of linzagolix in the treatm...

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Scientists launch study to find out if COVID-19 vaccines are causing period changes after hundreds of women notice irregularities Dr Kathryn Clancy and Dr Katherine Lee said they both experienced abnormal periods after getting the COVID-19 vaccine When they described their experiences on Twitter, hundreds of women replied that their menstrual cycles were also abnormal following the shot Clancy and Lee have now launched a study, including a survey in which women can document their menstrual experiences after vaccination As of Monday, more than 25,000 women have completed the questionnaire Expe...

Accelerated cellular aging in depressed individuals associated with increased mortality risk Cells from healthy individuals with major depressive disorder were found to have higher than expected rates of methylation at specific sites on their DNA, when compared to cells from healthy individuals without MDD, according to a study by a multidisciplinary team of Walter Reed Army Institute of Research and University of California San Francisco scientists, in collaboration with others. Methylation is a process by which DNA is chemically modified at specific sites, resulting in changes in the expres...

Methylation Metrics in Severely Depressed Patients Suggest Accelerated Cellular Aging Source: RealPeopleGroup/Getty Images April 8, 2021 Cells from individuals with Major Depressive Disorder (MDD) were found to have higher than expected rates of methylation at specific sites on their DNA, when compared to cells from healthy individuals without MDD, according to a multidisciplinary team of University of California-San Francisco (UCSF) scientists, in collaboration with others. Methylation of particular sets of genes (DNA methylation clocks) typically changes in predictable ways as people age, b...