VUMC to lead national study to treat severe COVID complications
by Bill Snyder The Vanderbilt Institute for Clinical and Translational Research (VICTR) has been awarded a major federal grant to lead a national trial of treatments targeting the Renin Angiotensin Aldosterone System (RAAS) in patients hospitalized with COVID-19. Comprised of the hormones renin, angiotensin and aldosterone, RAAS is essential for the regulation of blood pressure and fluid balance. SARS-CoV-2, the virus that causes COVID-19, can disrupt this system, resulting in life-threatening complications, including pulmonary edema, thromboembolic complications and severe cardiac injury. Se...