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Puberty Blockers: A Blight on the Brain - Quadrant Online

Is it not odd that gender clinics appear unaware of the High Court's ruling that medical practitioners must inform recipients of puberty blockers' many deleterious side effects. Given the growing number of de-transitioners and the ongoing denial of cross-sex hormones' harm to developing brains, a lawyers' bonanza is inevitable ....

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"Daily Cannabidiol Administration for 10 Weeks Modulates Hippocampal an" by Valentina Lorenzetti, Eugene McTavish et al.

Introduction: Cannabis use is associated with brain functional changes in regions implicated in prominent neuroscientific theories of addiction. Emerging evidence suggests that cannabidiol (CBD) is neuroprotective and may reverse structural brain changes associated with prolonged heavy cannabis use. In this study, we examine how an ∼10-week exposure of CBD in cannabis users affected resting-state functional connectivity in brain regions functionally altered by cannabis use. Materials and Methods: Eighteen people who use cannabis took part in a ∼10 weeks open-label pragmatic trial of self-administered daily 200 mg CBD in capsules. They were not required to change their cannabis exposure patterns. Participants were assessed at baseline and post-CBD exposure with structural magnetic resonance imaging (MRI) and a functional MRI resting-state task (eyes closed). Seed-based connectivity analyses were run to examine changes in the functional connectivity of a priori regions the hippocampu ....

Cannabis Use Disorder , Resting State Functional Connectivity ,