In Bevacizumab to Aflibercept Switch, Monitor For Risks - Endocrinology Advisor
Patients switching from bevacizumab to aflibercept for DME therapy should be evaluated for several risk factors.
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Patients switching from bevacizumab to aflibercept for DME therapy should be evaluated for several risk factors.
The analysis of the DRCR Retina Network Protocol AC suggested cost savings occur with bevacizumab-first step therapy in eyes with DME, but the magnitude might not be as great as previously understood.
The Protocol AC study analyzed visual acuity gains and cost if patients with diabetic macular edema started on bevacizumab, which costs less, and switched to aflibercept later, explained Jennifer K. Sun, MD, MPH, associate professor of ophthalmology and chief of the Center for Clinical Eye Research and Trials, Harvard Medical School; and chair, DRCR Retina Network.
KOLOA, Hawaii — Ultra-widefield fluorescein angiography may enable more sensitive and specific methods to predict diabetic retinopathy worsening compared with standard FA, Paolo S. Silva, MD, said at Retina 2023.
No difference in visual acuity at 2 years with bevacizumab-first or upfront-aflibercept strategy