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Hereditary angioedema has received renewed attention in the past two decades, with the elucidation of the biochemical pathways resulting in bradykinin overproduction in patients with congenital C1esterase inhibitor (C1INH) deficiency, leading to recurrent attacks of tissue swelling due to uncontrolled vascular permeability.1 Oedema attacks affecting the lingual or laryngeal area can become lethal as a result of asphyxiation.2 Several new treatments have emerged, 143 years after Quincke s first description of hereditary angioedema and 15 years after the introduction of the first specific bradykinin B2 receptor inhibitor (icatibant). ....
Prophylaxis with anti-activated factor XII for hereditary angioedema thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.
Non-allergic rhinitis can be triggered by anything from weather to hormones to drugs. Dr Iseult Sheehan takes a look at the causes and treatment of ....
Unravelling the link between occupational inhalants and rheumatoid arthritis nzdoctor.co.nz - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nzdoctor.co.nz Daily Mail and Mail on Sunday newspapers.
References 1. Appelboom T. Hypothesis: Rubens one of the first victims of an epidemic of rheumatoid arthritis that started in the 16th-17th century? Rheumatology (Oxford) 2005;44(5):681–83. 2. Morotti A, Sollaku I, Franceschini F, et al. Systematic review and meta-analysis on the association of occupational exposure to free crystalline silica and rheumatoid arthritis. Clin Rev Allergy Immunol 2021; 2 March online. 3. Mehri F, Jenabi E, Bashirian S, et al. The association between occupational exposure to silica and risk of developing rheumatoid arthritis: A meta-analysis. Saf Health Work 2020;11(2):136–42. 4. Snorrason E. Rheumatoid arthritis and occupation. Acta Med Scand 1951;140(5):355–58. 5. Ilar A, Alfredsson L, Wiebert P, et al. Occupation and risk of developing rheumatoid arthritis: Results from a population-based case-control study. ....