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A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions -; such as cell types or tissues.
Date Time Researchers speed identification of DNA regions that regulate gene expression Corresponding author Yong Cheng, Ph.D., of the St. Jude Departments of Hematology and Computational Biology, helped develop a highly efficient method in identifying the genetic switches that regulate gene expression. St. Jude Children’s Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for treatment of disorders such as sickle cell disease and beta thalassemia. The research appears today in the journal Nature Gen...