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A team led by researchers from Mass Eye and Ear, a member of Mass General Brigham, reports the results of a phase I trial of a revolutionary stem cell treatment called cultivated autologous limbal epithelial cell transplantation (CALEC), which was found to be safe and well-tolerated over the short term in four patients with significant chemical burns in one eye.

Type 1 interferon is a major diver of cognitive impairment and memory loss in mouse models of Alzheimer's disease. Blocking IFN reversed both cognitive impairments and memory deficits in the animal models.

Alzheimer’s disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish