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New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation. ....

Burdun Iliya , Ad Neuroimaging Initiative , Nature Medicine , Mini Mental State Examination , Geriatric Depression Scale , Hachinski Ischemic Scale , Columbia Suicide Severity Rating Scale , Scale Cognitive Subscale ,

Personalized rTMS Promising for Early Alzheimer's

Personalized repetitive transcranial magnetic stimulation targeting the hippocampal network improves cognitive and functional performance in early Alzheimer's. ....

Soult Ukpyolsi , South Korea , Kyongsang Namdo , Young Hee Jung , Hanyang University , Department Of Neurology , Myongji Hospital , Scale Cognitive Subscale , Clinical Dementia Rating Sum , Seoul Instrumental Activity Daily Living ,

Natural Killer Cell Therapy Shows Promise in Alzheimer's

Data from a small phase I study show significant clinical and biomarker activity of an investigational natural killer cell therapy in adults with AD, prompting a larger phase 2 trial. ....

United States , Shaheen Lakhan , Drug Administration , Medscape Medical , Clinical Trials , Clinical Dementia Rating Sum , Mini Mental State Examination , Scale Cognitive Subscale , Medscape Medical News , Alzheimers Disease , Lzheimer Disease , Natural Killer Cells , Nk Cells , Iological Marker , Blood Brain Barrier Bbb , Biologic Therapy , Healthcare And Medical Technology , Ealth And Medical Tech , Ealth And Med Tech , Ealth And Medical Technology , Biomedical Technology , Mild Cognitive Impairment , Cognitive Impairm ,

FDA Panel Backs Traditional Approval of Lecanemab for Alzheimer Disease

An FDA committee voted unanimously that lecanemab-irmb (Leqembi) shows clinical benefit for the treatment of Alzheimer disease. ....

Drug Administration , Central Nervous System Drugs Advisory Committee , Priority Review , Biologics License Application , Clinical Dementia Rating Sum , Scale Cognitive Subscale ,

FDA Panel Backs Traditional Approval of Lecanemab for Alzheimer Disease

An FDA committee voted unanimously that lecanemab-irmb (Leqembi) shows clinical benefit for the treatment of Alzheimer disease. ....

Drug Administration , Central Nervous System Drugs Advisory Committee , Priority Review , Biologics License Application , Clinical Dementia Rating Sum , Scale Cognitive Subscale ,