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Sio Gene Therapies Announces Positive Six-Month Follow-Up Data from Low-Dose Cohort of Phase ...


Press release content from Globe Newswire. The AP news staff was not involved in its creation.
Sio Gene Therapies Announces Positive Six-Month Follow-Up Data from Low-Dose Cohort of Phase .
Sio Gene TherapiesDecember 15, 2020 GMT
-  Generally well-tolerated with a favorable safety profile in five patients
-  Serum beta-galactosidase enzyme activity increased in all patients at all timepoints between Day 7 and Month 6, representing an approximate doubling in enzyme activity after gene transfer
-  At Month 6, enzyme activity restored to 23-57% (mean: 38%) of normal reference levels
-  All five children demonstrated signs of clinical disease stability as assessed by Vineland-3 Growth Scale Value, Upright and Floor Mobility, and Clinical Global Impression (CGI) scales ....

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Detailed text transcripts for TV channel - MSNBC - 20110319:14:19:00

Bill, let s get to the perspective here. i want people to understand this. japan raised the level of the crisis from a four to a five out of a scale of seven. five was three mile island, chernobyl was a 7. how would you rate the situation? i think a five is an appropriate scale value right now for the scale. this scale is like a richter scale for earthquakes. there is a lot of lat constitute between five and six. this accident is probably getting more severe than three mile island but not ten times as severe which would be a level six. that is a reasonable value right now. you are indicating exponential difference in these numbers. that s the scale. your biggest concern right now, bill, is what? ....

Richter Scale , Three Mile Island , Scale Value ,