Page 2 - Sci Rev News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Credit: @Science China Press Cancer is the second leading cause of death in the world. The number of deaths and incidences is increasing each year. The metal-based anticancer drugs were used clinically worldwide, but suffer from poor selectivity, serious side effects and drug resistance. Tumor-targeting drug development is the basis for precise cancer treatment. Recently, Professor Hongke Liu of Nanjing Normal University, Professor Jing Zhao and Academician Zijian Guo of Nanjing University have made breakthrough achievements in anticancer drug development. They proposed a "bio-orthogonally c...

 E-Mail IMAGE: (a) cellular uptake, (b) endosomal escape, (c) GSH depletion contributed by tetrasulfide-induced GSH oxidation and zinc-mediated inhibition of GR and GSSG reduction, (d) GAPDH deactivation, (e) increased MMP, (f) mTORC1... view more  Credit: @Science China Press Delivery of genetic molecules such as mRNA into cells is vital with important applications such as vaccine development. Various agents have been developed for mRNA delivery. However, conventional mRNA nanocarriers mainly focus on their physical interaction with mRNA molecules, or protection / delivery of mRNA,...

 E-Mail IMAGE: (a) Schematic drawings of the sample preparation processes. (b) (i) Cryo-EM image of the Ca-Cl crystals in the ultra-thin reduced graphene oxide (rGO) membrane. (ii) Diffraction pattern of a typical... view more  Credit: @Science China Press Calcium ions are presented in rocks, bones, shells, biominerals, geological deposits, ocean sediments, and many other important materials. Calcium ions also play major roles in the retention of carbon dioxide in natural waters, water hardness, signal transduction and tissue generation. As one of the alkaline earth metals, the calc...

 E-Mail IMAGE: (a) Theoretical output potential, specific capacity and energy density for the KO2 and other typical K-ion battery cathodes. (b) XRD pattern and TEM images of KO2-RuO2@rGO cathode composites. The XRD... view more  Credit: @Science China Press There is an urgent need for high-energy-density rechargeable batteries to further satisfy the ever-growing demand for electrical energy storage devices. Triggering the O-related anionic redox activities (e.g. typical Li/Na/K-O2 battery, and Li/Na-rich cathodes) have been regarded as the most promising capacity-boosting strategy f...