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UNC-Chapel Hill scientists investigated blood samples from children enrolled in a dengue vaccine trial to identify the specific kinds of antibody responses that

Scientists Discover How Dengue Vaccine Fails to Protect Against Disease June 23, 2021 UNC School of Medicine scientists led by Aravinda de Silva, PhD, identified the small subpopulation of antibodies in vaccinated children that correlate with protection against dengue fever. This research should help shape better vaccines for one of the most widespread infectious diseases in the world. Aravinda de Silva, PhD CHAPEL HILL, NC – Developing a viable vaccine against dengue virus has proved difficult because the pathogen is actually four different virus types, or serotypes. Unless a vaccine prote...

 E-Mail IMAGE: Image shows cells with oil droplet-like 'NORAD-Pumilio bodies' in red and nucleus in blue. Credit: Mahmoud Elguindy view more  Credit: Mahmoud Elguindy DALLAS - June 9, 2021 - A phenomenon in which an RNA named NORAD drives a protein named Pumilio to form liquid droplets in cells, much like oil in water, appears to tightly regulate the activity of Pumilio. A new study led by UT Southwestern scientists suggests that such RNA-driven "phase separation," in turn, protects against genome instability, premature aging, and neurodegenerative diseases, and may represent a prev...

Research brief: The study is based on near-real-time data from U.S. emergency medical service calls.

UCLA: Overdose Deaths Up 42% In 2020; Largest Increases Among Black And Latino Communities - La Cañada Flintridge, CA - Based on cases handled by emergency medical services, the number of people in the U.S. who died due to drug overdoses was 42% higher in ...