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Loss of abdominal fat may be key to reversing prediabetes

Prediabetes is a condition that precedes type 2 diabetes and increases the risk of heart attack, kidney and eye disease, and several types of cancer. Currently, there is no approved drug therapy for prediabetes available.

Germany , Munich , Bayern , German , Andreas-birkenfeld , Megan-craig , Arvid-sandforth , Institute-of-diabetes-research , Institute-for-diabetes-research , Department-of-diabetology , German-center , Diabetes-research

Targeted use of ultrasound technology can lead to significant changes in brain function

The targeted use of ultrasound technology can bring about significant changes in brain function that could pave the way towards treatment of conditions such as depression, addiction, or anxiety, a new study suggests.

United-kingdom , Lily-ramsey , Elsa-fouragnan , Nature-communications , University-hospitals-plymouth , University-of-plymouth , University-of-oxford , Radboud-university-nijmegen , University-college-london , United-kingdom-research , Senior-author , Associate-professor

Cardio or cerebrovascular mortality of AF patients has declined in the UK over 16 years

Patients living with one of the UK's most common heart rhythm conditions are 50% less likely to die from a heart attack or stroke than they were at the start of the millennium, new research has found.

United-kingdom , British , Jianhua-wu , Lily-ramsey , Leeds-institute-for-data-analytics , University-of-leeds , British-heart-foundation , Health-data-science , Senior-author , Cardiovascular-medicine , Honorary-consultant-cardiologist , Leeds-institute

Diabetes drug promotes longevity by stimulating the body's production of ether lipids

Metformin, the most commonly used drug to treat type 2 diabetes, not only lowers blood sugar levels but has revealed to extend lifespan in C. Elegans an animal model that shares similar metabolic systems with humans and are often used to model human diseases.

Massachusetts , United-states , G-lucydalila-cedillo , Adebanjo-adedoja , Khoi-dao , Yifei-zhou , Alexandera-soukas , Zhaozhi-li , Sainan-li , Seanp-curran , Sudeshna-das , Lukem-murphy

Scientists map how worm brain encodes behavior

To understand the full relationship between brain activity and behavior, scientists have needed a way to map this relationship for all of the neurons across a whole brain-;a so far insurmountable challenge.

Vikash-mansinghka , Cassi-estrem , Netta-cohen , Saba-baskoylu , Jungsoo-kim , Danielle-ellis , Matthew-gomes , Steven-flavell , Talya-kramer , Eric-bueno , Ziyu-wang , Adam-atanas

New pathway for HIV to enter nucleus of healthy cells identified

A study published on August 10, 2023 in the journal Nature Communications has identified a new pathway that human immune deficiency virus (HIV) uses to enter the nucleus of a healthy cell, where it can then replicate and go on to invade other cells.

Germany , Italy , New-york , United-states , Touro-college , Aurelio-lorico , Danielle-ellis , Alan-kadish , Denis-corbeil , Touro-university-nevada-college-of-osteopathic-medicine , Touro-university-president , Nature-communications

New treatment approach shows promise in reversing hormone resistance in breast cancer

A collaborative study between LSU Health New Orleans School of Medicine, the University of Rochester and Cellestia Biotech AG, a biopharmaceutical company headquartered in Basel, Switzerland, provides compelling evidence that combining an investigational oral drug with standard-of-care medications reverts hormone resistance and increases Rx effectiveness in experimental models of estrogen-receptor positive (ER+) and triple-negative breast cancers (TNBC), respectively.

Switzerland , United-states , American , Jovanny-zabaleta , Giulia-monticone , Fokhrul-hossain , Luis-del-valle , Samarpan-majumder , Dorota-wyczechowska , Danielle-ellis , Lucio-miele , University-of-rochester

Yale researchers create "humanized" liver in living mice to study chronic liver diseases

Yale researchers have created a functional "humanized" liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States.

United-states , Richard-flavell , Eleanna-kaffe , Danielle-ellis , Flavell-lab , Howard-hughes-medical-institute , Senior-author , Sterling-professor , Yale-school , Howard-hughes-medical , Chronic , Iver

Study shows how NSAIDs exacerbate C. difficile infections

Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide?

Philadelphia , Pennsylvania , United-states , Lily-ramsey , Josephp-zackular , Laboratory-medicine-at-children-hospital-of-philadelphia , Science-advances , Joshua-soto-oca , Senior-author , Assistant-professor , Laboratory-medicine , Antibiotic