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PSV picked up a massive victory in Sevilla on Wednesday. Peter Bosz's side came back from a 2-0 scoreline to win 2-3 after a dramatic late winner from Ricardo Pepi. Ismael Saibari and an own goal from Nemanja Gudelj had brought PSV level. Peter Bosz made zero changes to the side that beat FC Twente 0-3 on Saturday in the Eredivisie. Noa Lang was not a part of the squad. The winger came on in Enschede for his first appearance in seven weeks due to a hamstring injury but has now suffered another setback.

PSV have their first win in the Champions League. The Eindhovenaren beat RC Lens 1-0 and still have chances of making the last 16 due to this crucial victory. It was PSV's first win in the main stage of the Champions League since December 2015, when they beat CSKA Moscow 2-1. They did not win any of the 17 matches they played since then.