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Ancestral dormant genes could be driving cancer

Ancestral dormant genes could be driving cancer
21 May 2021
Despite decades of research, cancer remains an enigma.
Conventional wisdom holds that cancer is driven by random mutations that create aberrant cells that run amok in the body.
In a new paper published this week in the journal
BioEssays, researchers from The Australian National University and Arizona State University challenge this model.
Instead, they argue cancer is a type of genetic throwback that progresses via a series of reversions to ancestral forms of life.
In contrast with the conventional model, the researchers say the distinctive capabilities of cancer cells are not primarily generated by mutations but are pre-existent and lie dormant in normal cells. ....

United States , Kimberly Bussey , Anneke Blackburn , Charley Lineweaver , Paul Davies , Australian National University , Arizona State University , Professors Charley Lineweaver , Serial Atavism Model , Professor Lineweaver , Associate Professor Blackburn , Strategic Communications Amp Public Affairs , ஒன்றுபட்டது மாநிலங்களில் , பால் டேவிஸ் , ஆஸ்திரேலிய தேசிய பல்கலைக்கழகம் , அரிசோனா நிலை பல்கலைக்கழகம் , மூலோபாய தகவல்தொடர்புகள் ஆம்ப் பொது வாழ்க்கைத்தொழில்கள் ,

Challenging the standard model of cancer

In spite of decades of research, cancer remains an enigma. Conventional wisdom holds that cancer is driven by random mutations that create aberrant cells that run amok in the body. In a new paper published this week in the journal BioEssays, Arizona and Australian researchers challenge this model by proposing that cancer is a type of genetic throwback, that progresses via a series of reversions to ancestral forms of life. ....

United States , Australian Capital Territory , Kimberly Bussey , Anneke Blackburn , Charles Lineweaver , Charley Lineweaver , Paul Davies , Australian National University , Arizona State University , Midwestern University , Precision Medicine Program , Arizona Cancer Evolution Center , Precision Medicine Program At Midwestern University , Research School Of Astronomy , Arizona State University Beyond Center , Research School Of Earth Sciences , John Curtin School Of Medical Research , Professor Paul Davies , Beyond Center , Fundamental Concepts , Serial Atavism Model , Cancer Evolution Center , Curtin School , Medical Research , Professor Charley Lineweaver , Research School ,