No Survival Benefit With Extended Lymphadenectomy in Muscle-Invasive Bladder Cancer
Extended versus standard lymphadenectomy also associated with greater morbidity
Stay updated with breaking news from Sethp Lerner. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
Extended versus standard lymphadenectomy also associated with greater morbidity
Concurrent radical cystectomy and extended lymph node dissection did not show benefit vs standard lymph node dissection in muscle invasive urothelial cancer.
Analysis of molecular subtypes of muscle-invasive bladder cancer can predict if a tumor is likely to respond to chemotherapy before surgery but is not associated with differences in survival.
Extended lymphadenectomy at the time of radical cystectomy did not produce a significant improvement in disease-free survival (DFS) or overall survival (OS) vs standard lymphadenectomy for patients with muscle-invasive bladder cancer.
An extended lymphadenectomy – removal of additional lymph nodes beyond the extent of the standard procedure – in patients undergoing radical cystectomy (removal of bladder and nearby tissues) because of clinically localized muscle-invasive bladder cancer provides no patient benefit as measured by disease-free survival or overall survival times.