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Cryogenic electron microscopy represents a revolutionary improvement in our ability to see biological molecules. Since its early development in the 70s it has become an important tool for understanding life at the tiniest scales.
-in -class SK2 selective inhibitor targeting multiple indications with positive Phase 2 COVID-19 data and an ongoing Phase 2/3 program for COVID-19 and Phase 2 studies for prostate cancer and cholangiocarcinoma ongoing; (iii) RHB-107 (upamostat), a serine protease inhibitor in a U.S. Phase 2/3 study as treatment for symptomatic COVID-19, and targeting multiple other cancer and inflammatory gastrointestinal diseases; (iv) RHB-104, with positive results from a first Phase 3 study for Crohn's disease; (v) RHB-102 (Bekinda ®), with positive results from a Phase 3 study for acute gastroenterit...
New high-tech lab at Fred Hutch creates 3D maps of proteins to aid therapeutics and vaccine research April 24, 2021 at 12:10 am Assistant Professor Melody Campbell prepares a sample in the Shared Resources Cryo-EM Lab at the Fred Hutchinson Cancer Research Center in Seattle. (Fred Hutch Photo) Dr. Melody Campbell was an undergraduate student when she first noticed the beauty and power of cryogenic electron microscopy (cryo-EM), a technique that uses extreme temperatures and an electron microscope to create 3D maps of proteins. The image was stunning, and Campbell decided in that moment to foc...
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Essential workers illustrate the Heart of the Hutch While buildings remain more than half empty, hundreds of people keep science going and campus running amid pandemic Isma Lubega stands in front of his car in Kampala, Uganda. Lubega is the driver for the UCI-Fred Hutch Collaboration, a program born out of a longstanding relationship between Fred Hutch’s Global Oncology program and the Uganda Cancer Institute. Photo courtesy of Raquel Sanchez / Fred Hutch Global Oncology Heart of the Hutch: Essential Worker edition We have been profiling people who illustrate the cul...